Serum factors can modulate the developmental clock of gamma- to beta-globin gene switching in somatic cell hybrids.

The fusion of human fetal erythroid (HFE) cells with mouse erythroleukemia (MEL) cells produces stable synkaryons (HFE x MEL) which can be monitored for extended periods of time in culture. Initially these hybrids express a human fetal globin program (gamma >> beta), but after weeks or months...

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Bibliografiske detaljer
Main Authors: Zitnik, G, Li, Q, Stamatoyannopoulos, G, Papayannopoulou, T
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC360113/
https://ncbi.nlm.nih.gov/pubmed/8336721
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