Serum factors can modulate the developmental clock of gamma- to beta-globin gene switching in somatic cell hybrids.
The fusion of human fetal erythroid (HFE) cells with mouse erythroleukemia (MEL) cells produces stable synkaryons (HFE x MEL) which can be monitored for extended periods of time in culture. Initially these hybrids express a human fetal globin program (gamma >> beta), but after weeks or months in cul...
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| Wydane w: | Mol Cell Biol |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
1993
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8336721/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.4844-4851.1993 |
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