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Role of gene order in developmental control of human gamma- and beta-globin gene expression.

To determine the effect of gene order on globin gene developmental regulation, we produced transgenic mice containing two tandemly arranged gamma- or beta-globin or gamma beta- and beta gamma-globin genes linked to a 2.5-kb cassette containing sequences of the locus control region (LCR). Analysis of...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Peterson, K R, Stamatoyannopoulos, G
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360110/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8336720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.4836-4843.1993
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