Role of gene order in developmental control of human gamma- and beta-globin gene expression.

To determine the effect of gene order on globin gene developmental regulation, we produced transgenic mice containing two tandemly arranged gamma- or beta-globin or gamma beta- and beta gamma-globin genes linked to a 2.5-kb cassette containing sequences of the locus control region (LCR). Analysis of...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Peterson, K R, Stamatoyannopoulos, G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360110/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8336720/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.8.4836-4843.1993
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