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Anti-Allergic Cromones Inhibit Histamine and Eicosanoid Release from Activated Human and Murine Mast Cells by Releasing Annexin A1

BACKGROUND AND PURPOSE: Although the ‘cromones’ (di-sodium cromoglycate and sodium nedocromil) are used to treat allergy and asthma, their ‘mast cell stabilising’ mechanism of pharmacological action has never been convincingly explained. Here, we investigate the hypothesis that these drugs act by st...

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Bibliografiska uppgifter
Huvudupphovsmän: Yazid, Samia, Sinniah, Ajantha, Solito, Egle, Calder, Virginia, Flower, Rod J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601088/
https://ncbi.nlm.nih.gov/pubmed/23527056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058963
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