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Anti-allergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization
OBJECTIVES: The anti-allergic ‘mast cell stabilising’ cromones release the anti-inflammatory protein annexin A1 (Anx-A1) from U937 cells. These drugs also inhibit polymorphonuclear leukocyte (PMN) trafficking. Since PMN can synthesise and release large amounts of Anx-A1, we hypothesised that a simil...
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Publicado no: | Arterioscler Thromb Vasc Biol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365443/ https://ncbi.nlm.nih.gov/pubmed/20558817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.209536 |
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