A phase 1b study of humanized KS-interleukin-2 (huKS-IL2) immunocytokine with cyclophosphamide in patients with EpCAM-positive advanced solid tumors

BACKGROUND: Humanized KS-interleukin-2 (huKS-IL2), an immunocytokine with specificity for epithelial cell adhesion molecule (EpCAM), has demonstrated favorable tolerability and immunologic activity as a single agent. METHODS: Phase 1b study in patients with EpCAM-positive advanced solid tumors to de...

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Detalhes bibliográficos
Main Authors: Connor, Joseph P, Cristea, Mihaela C, Lewis, Nancy L, Lewis, Lionel D, Komarnitsky, Philip B, Mattiacci, Maria R, Felder, Mildred, Stewart, Sarah, Harter, Josephine, Henslee-Downey, Jean, Kramer, Daniel, Neugebauer, Roland, Stupp, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600662/
https://ncbi.nlm.nih.gov/pubmed/23320927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-20
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