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Suppression of src transformation by overexpression of full-length GTPase-activating protein (GAP) or of the GAP C terminus.

Overexpression of the full-length GTPase-activating protein (GAP) has recently been shown to suppress c-ras transformation of NIH 3T3 cells but not v-ras transformation (36). Here, we show that focus formation induced by c-src was inhibited by approximately 80% when cotransfected with a plasmid enco...

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Udgivet i:Mol Cell Biol
Principais autores: DeClue, J E, Zhang, K, Redford, P, Vass, W C, Lowy, D R
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360064/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2017179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.5.2819-2825.1991
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