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Generating Contrast in Hyperpolarized (13)C MRI using Ligand-Receptor Interactions

We report the imaging of β-cyclodextrin/benzoic acid binding at 14T using hyperpolarized (13)C magnetic resonance (MR). Benzoic acid was polarized using a dynamic nuclear polarization (DNP) approach and combined with β-cyclodextrin in aqueous solution. As anticipated, decreases in the spin-lattice r...

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Detalhes bibliográficos
Main Authors: Keshari, Kayvan R., Kurhanewicz, John, Macdonald, Jeffrey M., Wilson, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600417/
https://ncbi.nlm.nih.gov/pubmed/22655289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2an35406c
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