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Generation of hyperpolarized substrates by secondary labeling with [1,1-(13)C] acetic anhydride

In this manuscript, the remarkable NMR signal enhancement that can be provided by dynamic nuclear polarization (DNP) was combined with the reactivity of acetic anhydride with amines to perform rapid, high SNR analyses of amino acid mixtures and to hyperpolarize new biomolecules of interest. [1,1-(13...

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Detalhes bibliográficos
Main Authors: Wilson, David M., Hurd, Ralph E., Keshari, Kayvan, Van Criekinge, Mark, Chen, Albert P., Nelson, Sarah J., Vigneron, Daniel B., Kurhanewicz, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654026/
https://ncbi.nlm.nih.gov/pubmed/19276112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810190106
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