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Generation of hyperpolarized substrates by secondary labeling with [1,1-(13)C] acetic anhydride

In this manuscript, the remarkable NMR signal enhancement that can be provided by dynamic nuclear polarization (DNP) was combined with the reactivity of acetic anhydride with amines to perform rapid, high SNR analyses of amino acid mixtures and to hyperpolarize new biomolecules of interest. [1,1-(13...

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Bibliographic Details
Main Authors: Wilson, David M., Hurd, Ralph E., Keshari, Kayvan, Van Criekinge, Mark, Chen, Albert P., Nelson, Sarah J., Vigneron, Daniel B., Kurhanewicz, John
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654026/
https://ncbi.nlm.nih.gov/pubmed/19276112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810190106
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