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A Hydrogen Peroxide-Responsive Hyperpolarized (13)C MRI Contrast Agent
We report a new reaction-based approach for the detection of hydrogen peroxide (H(2)O(2)) using hyperpolarized (13)C magnetic resonance imaging ((13)C MRI) and the H(2)O(2)-mediated oxidation of α-ketoacids to carboxylic acids. (13)C-benzoylformic acid ((13)C-BFA) reacts selectively with H(2)O(2) ov...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060273/ https://ncbi.nlm.nih.gov/pubmed/21366297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja111589a |
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