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Central dogma at the single-molecule level in living cells

Gene expression originates from individual DNA molecules within living cells. Like many single-molecule processes, gene expression and regulation are stochastic, that is, sporadic in time. This leads to heterogeneity in the messenger RNA and protein copy numbers in a population of cells with identic...

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Detalhes bibliográficos
Main Authors: Li, Gene-Wei, Xie, X. Sunney
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600414/
https://ncbi.nlm.nih.gov/pubmed/21776076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10315
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