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Quantifying E. coli proteome and transcriptome with single-molecule sensitivity in single cells

Protein and mRNA copy numbers vary from cell to cell in isogenic bacterial populations. However, these molecules often exist in low copy numbers, and are difficult to detect in single cells. Here we carried out quantitative system-wide analyses of protein and mRNA expression in individual cells with...

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Bibliografske podrobnosti
Main Authors: Taniguchi, Yuichi, Choi, Paul J., Li, Gene-Wei, Chen, Huiyi, Babu, Mohan, Hearn, Jeremy, Emili, Andrew, Xie, X. Sunney
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922915/
https://ncbi.nlm.nih.gov/pubmed/20671182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1188308
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