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Hydrogen-Exchange Mass Spectrometry for the Study of Intrinsic Disorder in Proteins
Amide hydrogen/deuterium exchange detected by mass spectrometry (HXMS) is seeing wider use for the identification of intrinsically disordered parts of proteins. In this review, we discuss examples of how discovery of intrinsically disordered regions and their removal can aid in structure determinati...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3600394/ https://ncbi.nlm.nih.gov/pubmed/23099262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2012.10.009 |
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