Evidence from mutation spectra that the UV hypermutability of xeroderma pigmentosum variant cells reflects abnormal, error-prone replication on a template containing photoproducts.

Ítems similars

• Abnormal, Error-Prone Bypass of Photoproducts by Xeroderma Pigmentosum Variant Cell Extracts Results in Extreme Strand Bias for the Kinds of Mutations Induced by UV Light
  per: McGregor, W. Glenn, et al.
  Publicat: (1999)
• Xeroderma pigmentosum variant cells are less likely than normal cells to incorporate dAMP opposite photoproducts during replication of UV-irradiated plasmids.
  per: Wang, Y C, et al.
  Publicat: (1991)
• Frequency of UV-induced neoplastic transformation of diploid human fibroblasts is higher in xeroderma pigmentosum cells than in normal cells.
  per: Maher, V M, et al.
  Publicat: (1982)
• Xeroderma pigmentosum.
  per: Kobza, A, et al.
  Publicat: (1972)
• Xeroderma Pigmentosum
  per: Schwartz, B.
  Publicat: (1957)