Induction of cellular p53 activity by DNA-damaging agents and growth arrest.
The tumor suppressor p53 can function as a sequence-specific transcription factor and is required for activation by ionizing radiation (IR) of one or more downstream effector genes, such as the human GADD45 gene. One important consequence of IR that is probably mediated by these downstream effector...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359974/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8321226/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.7.4242-4250.1993 |
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