Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes.

We have mapped a number of mutations at the DNA sequence level in genes encoding the largest (RpII215) and second-largest (RpII140) subunits of Drosophila melanogaster RNA polymerase II. Using polymerase chain reaction (PCR) amplification and single-strand conformation polymorphism (SSCP) analysis,...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Chen, Y, Weeks, J, Mortin, M A, Greenleaf, A L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8321225/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.7.4214-4222.1993
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