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Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes.

We have mapped a number of mutations at the DNA sequence level in genes encoding the largest (RpII215) and second-largest (RpII140) subunits of Drosophila melanogaster RNA polymerase II. Using polymerase chain reaction (PCR) amplification and single-strand conformation polymorphism (SSCP) analysis,...

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書目詳細資料
發表在:	Mol Cell Biol
Principais autores:	Chen, Y, Weeks, J, Mortin, M A, Greenleaf, A L
格式:	Artigo
語言:	Inglês
出版:	Taylor & Francis 1993
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359971/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8321225/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.7.4214-4222.1993
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Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes.

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