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Silencing of STIM1 attenuates hypoxia-induced PASMCs proliferation via inhibition of the SOC/Ca(2+)/NFAT pathway
BACKGROUND: Stromal interaction molecule 1 (STIM1) is a newly discovered Ca(2+) sensor on the endoplasmic reticulum which is an indispensable part in the activation of store-operated Ca(2+) channels (SOC). Recent studies demonstrate that SOC of pulmonary smooth muscle cells (PASMCs) were upregulated...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3599439/ https://ncbi.nlm.nih.gov/pubmed/23289723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-2 |
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