Induction of human fetal hemoglobin expression by adenosine-2’,3’-dialdehyde

BACKGROUND: Pharmacologic reactivation of fetal hemoglobin expression is a promising strategy for treatment of sickle cell disease and β-thalassemia. The objective of this study was to investigate the effect of the methyl transferase inhibitor adenosine-2’,3’-dialdehyde (Adox) on induction of human...

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Hlavní autoři: He, Yinghong, Rank, Gerhard, Zhang, Miaomiao, Ju, Junyi, Liu, Ronghua, Xu, Zhen, Brown, Fiona, Cerruti, Loretta, Ma, Chi, Tan, Renxiang, Jane, Stephen M, Zhao, Quan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3599103/
https://ncbi.nlm.nih.gov/pubmed/23316703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-14
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