The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potency.
The erbB-2 gene product, gp185erbB-2, unlike the structurally related epidermal growth factor (EGF) receptor (EGFR), exhibits constitutive kinase and transforming activity. We used a chimeric EGFR/erbB-2 expression vector to compare the mitogenic signaling pathway of the erbB-2 kinase with that of t...
Zapisane w:
| Wydane w: | Mol Cell Biol |
|---|---|
| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
1991
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359891/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1672440/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.4.2040-2048.1991 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|