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Anti-Analgesic Effect of the Mu/Delta Opioid Receptor Heteromer Revealed by Ligand-Biased Antagonism

Delta (DOR) and mu opioid receptors (MOR) can complex as heteromers, conferring functional properties in agonist binding, signaling and trafficking that can differ markedly from their homomeric counterparts. Because of these differences, DOR/MOR heteromers may be a novel therapeutic target in the tr...

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Bibliografische gegevens
Hoofdauteurs: Milan-Lobo, Laura, Enquist, Johan, van Rijn, Richard M., Whistler, Jennifer L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598907/
https://ncbi.nlm.nih.gov/pubmed/23554887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058362
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