Platelet-derived growth factor increases the in vivo activity of phospholipase C-gamma 1 and phospholipase C-gamma 2.

Upon binding to its cell surface receptor, platelet-derived growth factor (PDGF) causes the tyrosine phosphorylation of phospholipase C-gamma 1 (PLC-gamma 1) and stimulates the production of diacylglycerol and inositol 1,4,5-triphosphate. We showed that following stimulation by PDGF, rat-2 cells ove...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Sultzman, L, Ellis, C, Lin, L L, Pawson, T, Knopf, J
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359888/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2005895/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.4.2018-2025.1991
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