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Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection
BACKGROUND: Type I interferon (IFN) treatment of some cells, including dendritic cells, macrophages and monocytic THP-1 cells, restricts HIV-1 infection and prevents viral cDNA accumulation. Sterile alpha motif and HD domain protein 1 (SAMHD1), a dGTP-regulated deoxynucleotide triphosphohydrolase, r...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3598776/ https://ncbi.nlm.nih.gov/pubmed/23442224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-23 |
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