Cell cycle-dependent strand bias for UV-induced mutations in the transcribed strand of excision repair-proficient human fibroblasts but not in repair-deficient cells.

To study the effect of nucleotide excision repair on the spectrum of mutations induced in diploid human fibroblasts by UV light (wavelength, 254 nm), we synchronized repair-proficient cells and irradiated them when the HPRT gene was about to be replicated (early S phase) so that there would be no ti...

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Autores principales: McGregor, W G, Chen, R H, Lukash, L, Maher, V M, McCormick, J J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC359877/
https://ncbi.nlm.nih.gov/pubmed/2005888
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