Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization

Interleukin 2-inducible T cell kinase (ITK) influences T cell signaling by coordinating actin polymerization and polarization as well as recruitment of kinases and adapter proteins. ITK regulates multiple steps of HIV-1 replication, including virion assembly and release. Fluorescent microscopy was u...

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Autores principales: Schiralli Lester, Gillian M., Akiyama, Hisashi, Evans, Erica, Singh, Juswinder, Gummuluru, Suryaram, Henderson, Andrew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598624/
https://ncbi.nlm.nih.gov/pubmed/23260110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.11.015
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