Strength of T cell signaling regulates HIV-1 replication and establishment of latency

A major barrier to curing HIV-1 is the long-lived latent reservoir that supports re-emergence of HIV-1 upon treatment interruption. Targeting this reservoir will require mechanistic insights into the establishment and maintenance of HIV-1 latency. Whether T cell signaling at the time of HIV-1 infect...

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Publicado en:PLoS Pathog
Autores principales: Gagne, Matthew, Michaels, Daniel, Schiralli Lester, Gillian M., Gummuluru, Suryaram, Wong, Wilson W., Henderson, Andrew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6548398/
https://ncbi.nlm.nih.gov/pubmed/31116788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007802
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