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HIV-1 replicates and persists in vaginal epithelial dendritic cells

HIV-1 acquisition occurs most commonly after sexual contact. To establish infection, HIV-1 must infect cells that support high-level replication, namely CD4(+) T cells, which are absent from the outermost genital epithelium. Dendritic cells (DCs), present in mucosal epithelia, potentially facilitate...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Pena-Cruz, Victor, Agosto, Luis M., Akiyama, Hisashi, Olson, Alex, Moreau, Yvetane, Larrieux, Jean-Robert, Henderson, Andrew, Gummuluru, Suryaram, Sagar, Manish
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063466/
https://ncbi.nlm.nih.gov/pubmed/29723162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI98943
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