Selective targeting of ITK blocks multiple steps of HIV replication

Treatment for HIV has relied on the use of antiretroviral agents that can be subject to the development of resistant viruses. The study of inhibitors directed against cellular proteins required for HIV replication is therefore of growing interest. Inducible T cell kinase (ITK) is a Tec family tyrosi...

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Main Authors: Readinger, Julie A., Schiralli, Gillian M., Jiang, Jian-Kang, Thomas, Craig J., August, Avery, Henderson, Andrew J., Schwartzberg, Pamela L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2008
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365562/
https://ncbi.nlm.nih.gov/pubmed/18443296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709659105
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