Selective targeting of ITK blocks multiple steps of HIV replication

Treatment for HIV has relied on the use of antiretroviral agents that can be subject to the development of resistant viruses. The study of inhibitors directed against cellular proteins required for HIV replication is therefore of growing interest. Inducible T cell kinase (ITK) is a Tec family tyrosi...

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Autori principali: Readinger, Julie A., Schiralli, Gillian M., Jiang, Jian-Kang, Thomas, Craig J., August, Avery, Henderson, Andrew J., Schwartzberg, Pamela L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365562/
https://ncbi.nlm.nih.gov/pubmed/18443296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709659105
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