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A Consensus Mechanism for Radical SAM-Dependent Dehydrogenation? BtrN Contains Two [4Fe–4S] Clusters()

BtrN catalyzes the two-electron oxidation of the C3 secondary alcohol of 2-deoxy-scyllo-inosamine to the corresponding ketone, and is a member of a subclass of radical S-adenosylmethionine (SAM) enzymes called radical SAM (RS) dehydrogenases. As do all RS enzymes, BtrN contains a [4Fe–4S] cluster th...

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Detalhes bibliográficos
Main Authors: Grove, Tyler L., Ahlum, Jessica H., Sharma, Priya, Krebs, Carsten, Booker, Squire J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598582/
https://ncbi.nlm.nih.gov/pubmed/20377206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9022126
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