Apoptosis rate and transcriptional response of pancreatic islets exposed to the PPAR gamma agonist Pioglitazone

To explore the molecular pathways underlying thiazolidinediones effects on pancreatic islets in conditions mimicking normo- and hyperglycemia, apoptosis rate and transcriptional response to Pioglitazone at both physiological and supraphysiological glucose concentrations were evaluated. Adult rat isl...

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Detalhes bibliográficos
Main Authors: Lamounier, Rodrigo N, Coimbra, Cassio N, White, Peter, Costal, Flavia L, Oliveira, Leonardo S, Giannella-Neto, Daniel, Kaestner, Klaus H, Corrêa-Giannella, Maria Lúcia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598339/
https://ncbi.nlm.nih.gov/pubmed/23298687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-5996-5-1
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