The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats

BACKGROUND: Activation of peroxisome proliferator-activated receptor (PPAR)gamma is associated with bone loss and increased fracture risk, while PPARalpha activation seems to have positive skeletal effects. To further explore these effects we have examined the effect of the PPARalpha agonists fenofi...

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Detalhes bibliográficos
Main Authors: Stunes, Astrid K, Westbroek, Irene, Gustafsson, Björn I, Fossmark, Reidar, Waarsing, Jan H, Eriksen, Erik F, Petzold, Christiane, Reseland, Janne E, Syversen, Unni
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127763/
https://ncbi.nlm.nih.gov/pubmed/21615901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6823-11-11
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