Overproduction of v-Myc in the nucleus and its excess over Max are not required for avian fibroblast transformation.
The cellular proto-oncogene c-myc can acquire transforming potential by a number of different means, including retroviral transduction. The transduced allele generally contains point mutations relative to c-myc and is overexpressed in infected cells, usually as a v-Gag-Myc fusion protein. Upon synth...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8497274/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3623-3631.1993 |
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