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Overproduction of v-Myc in the nucleus and its excess over Max are not required for avian fibroblast transformation.

The cellular proto-oncogene c-myc can acquire transforming potential by a number of different means, including retroviral transduction. The transduced allele generally contains point mutations relative to c-myc and is overexpressed in infected cells, usually as a v-Gag-Myc fusion protein. Upon synth...

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Bibliographische Detailangaben
Hauptverfasser: Tikhonenko, A T, Hartman, A R, Linial, M L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC359831/
https://ncbi.nlm.nih.gov/pubmed/8497274
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