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Overproduction of v-Myc in the nucleus and its excess over Max are not required for avian fibroblast transformation.

The cellular proto-oncogene c-myc can acquire transforming potential by a number of different means, including retroviral transduction. The transduced allele generally contains point mutations relative to c-myc and is overexpressed in infected cells, usually as a v-Gag-Myc fusion protein. Upon synth...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Tikhonenko, A T, Hartman, A R, Linial, M L
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359831/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8497274/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.6.3623-3631.1993
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