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Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3

TCR-induced NF-AT activation leads to the up-regulation of multiple genes involved in T cell anergy. Since NF-AT is also involved in T cell activation, we have endeavored to dissect TCR-induced activating and inhibitory genetic programs. This approach revealed roles for the early growth response (Eg...

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Hlavní autoři: Collins, Sam, Lutz, Michael A., Zarek, Paul E., Anders, Robert A., Kersh, Gilbert J., Powell, Jonathan D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598016/
https://ncbi.nlm.nih.gov/pubmed/18203138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200737157
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