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Novel mutants of NAB corepressors enhance activation by Egr transactivators.
The NGFI-A binding corepressors NAB1 and NAB2 interact with a conserved domain (R1 domain) within the Egr1/NGFI-A and Egr2/Krox20 transactivators, and repress the transcription of Egr target promoters. Using a novel adaptation of the yeast two-hybrid screen, we have identified several point mutation...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1998
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170927/ https://ncbi.nlm.nih.gov/pubmed/9774344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.20.6010 |
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