The Presence of HIV-1 Tat Protein Second Exon Delays Fas Protein-mediated Apoptosis in CD4(+) T Lymphocytes: A POTENTIAL MECHANISM FOR PERSISTENT VIRAL PRODUCTION

HIV-1 replication is efficiently controlled by the regulator protein Tat (101 amino acids) and codified by two exons, although the first exon (1–72 amino acids) is sufficient for this process. Tat can be released to the extracellular medium, acting as a soluble pro-apoptotic factor in neighboring ce...

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Dades bibliogràfiques
Autors principals: López-Huertas, María Rosa, Mateos, Elena, Sánchez del Cojo, María, Gómez-Esquer, Francisco, Díaz-Gil, Gema, Rodríguez-Mora, Sara, López, Juan Antonio, Calvo, Enrique, López-Campos, Guillermo, Alcamí, José, Coiras, Mayte
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597804/
https://ncbi.nlm.nih.gov/pubmed/23364796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.408294
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