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Protein Kinase Cθ Is a Specific Target for Inhibition of the HIV Type 1 Replication in CD4(+) T Lymphocytes

Integration of HIV-1 genome in CD4(+) T cells produces latent reservoirs with long half-life that impedes the eradication of the infection. Control of viral replication is essential to reduce the size of latent reservoirs, mainly during primary infection when HIV-1 infects CD4(+) T cells massively....

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Main Authors: López-Huertas, María Rosa, Mateos, Elena, Díaz-Gil, Gema, Gómez-Esquer, Francisco, Sánchez del Cojo, María, Alcamí, José, Coiras, Mayte
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149330/
https://ncbi.nlm.nih.gov/pubmed/21669868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210443
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