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α-Synuclein Membrane Association Is Regulated by the Rab3a Recycling Machinery and Presynaptic Activity
α-Synuclein is an abundant presynaptic protein and a primary component of Lewy bodies in Parkinson disease. Although its pathogenic role remains unclear, in healthy nerve terminals α-synuclein undergoes a cycle of membrane binding and dissociation. An α-synuclein binding assay was used to screen for...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597785/ https://ncbi.nlm.nih.gov/pubmed/23344955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.439497 |
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