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STAT3 mediates resistance of CD44(+)CD24(−/low) breast cancer stem cells to tamoxifen in vitro

We sought to determine whether STAT3 mediated tamoxifen resistance of breast cancer stem cells in vitro. The capacities for mammosphere formation and STAT3 expression of CD44(+)CD24(−/low) MCF-7 and MCF-7 were observed. The CD44(+)CD24(−/low) subpopulation ratio and its sensitivity to adriamycin wer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Xiaoyan, Wang, Guozhu, Zhao, Yi, Liu, Xiaoan, Ding, Qiang, Shi, Jingping, Ding, Yin, Wang, Shui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Editorial Department of Journal of Biomedical Research 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597778/
https://ncbi.nlm.nih.gov/pubmed/23554768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.26.20110050
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