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STAT3 mediates resistance of CD44(+)CD24(−/low) breast cancer stem cells to tamoxifen in vitro

We sought to determine whether STAT3 mediated tamoxifen resistance of breast cancer stem cells in vitro. The capacities for mammosphere formation and STAT3 expression of CD44(+)CD24(−/low) MCF-7 and MCF-7 were observed. The CD44(+)CD24(−/low) subpopulation ratio and its sensitivity to adriamycin wer...

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Detalhes bibliográficos
Main Authors: Wang, Xiaoyan, Wang, Guozhu, Zhao, Yi, Liu, Xiaoan, Ding, Qiang, Shi, Jingping, Ding, Yin, Wang, Shui
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597778/
https://ncbi.nlm.nih.gov/pubmed/23554768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.26.20110050
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