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Secondary RNA structure and nucleotide specificity contribute to internal initiation mediated by the human tau 5′ leader

Mechanisms by which eukaryotic internal ribosomal entry sites (IRESs) initiate translation have not been well described. Viral IRESs utilize a combination of secondary/tertiary structure concomitant with sequence specific elements to initiate translation. Eukaryotic IRESs are proposed to utilize the...

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Detalhes bibliográficos
Main Authors: Veo, Bethany L., Krushel, Leslie A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597575/
https://ncbi.nlm.nih.gov/pubmed/22995835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.22181
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