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Secondary RNA structure and nucleotide specificity contribute to internal initiation mediated by the human tau 5′ leader
Mechanisms by which eukaryotic internal ribosomal entry sites (IRESs) initiate translation have not been well described. Viral IRESs utilize a combination of secondary/tertiary structure concomitant with sequence specific elements to initiate translation. Eukaryotic IRESs are proposed to utilize the...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597575/ https://ncbi.nlm.nih.gov/pubmed/22995835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.22181 |
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