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Identifying intrinsic and extrinsic determinants that regulate internal initiation of translation mediated by the FMR1 5' leader
BACKGROUND: Regulating synthesis of the Fragile X gene (FMR1) product, FMRP alters neural plasticity potentially through its role in the microRNA pathway. Cap-dependent translation of the FMR1 mRNA, a process requiring ribosomal scanning through the 5' leader, is likely impeded by the extensive...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2576346/ https://ncbi.nlm.nih.gov/pubmed/18922172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-89 |
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