Protein Malnutrition Induces Bone Marrow Mesenchymal Stem Cells Commitment to Adipogenic Differentiation Leading to Hematopoietic Failure

Protein malnutrition (PM) results in pathological changes that are associated with peripheral leukopenia, bone marrow (BM) hypoplasia and alterations in the BM microenvironment leading to hematopoietic failure; however, the mechanisms involved are poorly understood. In this context, the BM mesenchym...

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Main Authors: Cunha, Mayara Caldas Ramos, Lima, Fabiana da Silva, Vinolo, Marco Aurélio Ramirez, Hastreiter, Araceli, Curi, Rui, Borelli, Primavera, Fock, Ricardo Ambrósio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597562/
https://ncbi.nlm.nih.gov/pubmed/23516566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058872
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