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Protein Malnutrition Induces Bone Marrow Mesenchymal Stem Cells Commitment to Adipogenic Differentiation Leading to Hematopoietic Failure

Protein malnutrition (PM) results in pathological changes that are associated with peripheral leukopenia, bone marrow (BM) hypoplasia and alterations in the BM microenvironment leading to hematopoietic failure; however, the mechanisms involved are poorly understood. In this context, the BM mesenchym...

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Hlavní autoři: Cunha, Mayara Caldas Ramos, Lima, Fabiana da Silva, Vinolo, Marco Aurélio Ramirez, Hastreiter, Araceli, Curi, Rui, Borelli, Primavera, Fock, Ricardo Ambrósio
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597562/
https://ncbi.nlm.nih.gov/pubmed/23516566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058872
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