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ErbB3-binding protein EBP1 decreases ErbB2 levels via a transcriptional mechanism

Ectopic expression of EBP1, an ErbB3-interacting protein, reduces the expression of the ErbB2 protein and mRNA. However, the mechanism of EBP1-induced decrease in ErbB2 mRNA levels has not yet been determined. Since EBP1 affects both transcriptional and post-transcriptional processes, we evaluated t...

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Autors principals: GHOSH, ARUNDHATI, AWASTHI, SMITA, HAMBURGER, ANNE W.
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597558/
https://ncbi.nlm.nih.gov/pubmed/23242156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.2186
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