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Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylases

Ebp1, an ErbB3 binding protein that is a member of the proliferation-associated PA2G4 family, inhibits the proliferation and induces the differentiation of human ErbB positive breast and prostate cancer cell lines. Ebp1 binds the tumor suppressor retinoblastoma protein (Rb) both in vivo and in vitro...

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Detalhes bibliográficos
Main Authors: Zhang, Yuexing, Woodford, Nicholas, Xia, Xianmin, Hamburger, Anne W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153746/
https://ncbi.nlm.nih.gov/pubmed/12682367
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